ENZYME entry: EC 1.1.1.127

Accepted Name
2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase.
Alternative Name(s)
2-keto-3-deoxygluconate dehydrogenase.
Reaction catalysed
2-dehydro-3-deoxy-D-gluconate + NAD(+) <=> (4S)-4,6-dihydroxy-2,5-dioxohexanoate + NADH
Comment(s)
The enzyme from Pseudomonas acts equally well on NAD(+) or NADP(+), while those from Erwinia chrysanthemi and Escherichia coli are more specific for NAD(+).
Cross-references
BRENDA	1.1.1.127
EC2PDB	1.1.1.127
ExplorEnz	1.1.1.127
PRIAM enzyme-specific profiles	1.1.1.127
KEGG Ligand Database for Enzyme Nomenclature	1.1.1.127
IUBMB Enzyme Nomenclature	1.1.1.127
IntEnz	1.1.1.127
MEDLINE	Find literature relating to 1.1.1.127
MetaCyc	1.1.1.127
UniProtKB/Swiss-Prot	P50842, KDUD_BACSU;   Q05528, KDUD_DICD3;   P37769, KDUD_ECOLI;

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