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ENZYME entry: EC 1.1.1.136

Accepted Name
UDP-N-acetylglucosamine 6-dehydrogenase.
Alternative Name(s)
UDP-2-acetamido-2-deoxy-D-glucose:NAD oxidoreductase.
Reaction catalysed
UDP-N-acetyl-alpha-D-glucosamine + 2 NAD(+) + H(2)O <=> UDP-2-acetamido-2-deoxy-alpha-D-glucuronate + 2 NADH
Comment(s)
This enzyme participates in the biosynthetic pathway for UDP-alpha-D- ManNAc(3)NAcA (UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronic acid), an important precursor of B-band lipopolysaccharide.
Cross-references
BRENDA1.1.1.136
EC2PDB1.1.1.136
ExplorEnz1.1.1.136
PRIAM enzyme-specific profiles1.1.1.136
KEGG Ligand Database for Enzyme Nomenclature1.1.1.136
IUBMB Enzyme Nomenclature1.1.1.136
IntEnz1.1.1.136
MEDLINEFind literature relating to 1.1.1.136
MetaCyc1.1.1.136
UniProtKB/Swiss-Prot
G3XD94, UGND_PSEAE

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