ID   1.1.1.153
DE   Sepiapterin reductase.
CA   (1) 7,8-dihydrobiopterin + NADP(+) = sepiapterin + NADPH.
CA   (2) Tetrahydrobiopterin + 2 NADP(+) = 6-pyruvoyl-5,6,7,8-tetrahydropterin
CA   + 2 NADPH.
CC   -!- Catalyzes the final step in the de novo synthesis of
CC       tetrahydrobiopterin from GTP, with the other enzymes involved being
CC       EC 3.5.4.16 and EC 4.2.3.12.
DR   Q17QK8, SPRE_BOVIN ;  Q54GP3, SPRE_DICDI ;  P35270, SPRE_HUMAN ;
DR   Q8R536, SPRE_MERUN ;  Q64105, SPRE_MOUSE ;  P18297, SPRE_RAT   ;
DR   Q7ZY31, SPRE_XENLA ;  B0BML7, SPRE_XENTR ;
//