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ENZYME entry: EC 1.1.1.178

Accepted Name
3-hydroxy-2-methylbutyryl-CoA dehydrogenase.
Alternative Name(s)
2-methyl-3-hydroxybutyryl-CoA dehydrogenase.
Reaction catalysed
(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA + NAD(+) <=> 2-methylacetoacetyl-CoA + NADH
Comment(s)
Also acts, more slowly, on (2S,3S)-2-hydroxy-3-methylpentanoyl-CoA.
Cross-references
PROSITEPDOC00060
BRENDA1.1.1.178
EC2PDB1.1.1.178
ExplorEnz1.1.1.178
PRIAM enzyme-specific profiles1.1.1.178
KEGG Ligand Database for Enzyme Nomenclature1.1.1.178
IUBMB Enzyme Nomenclature1.1.1.178
IntEnz1.1.1.178
MEDLINEFind literature relating to 1.1.1.178
MetaCyc1.1.1.178
UniProtKB/Swiss-Prot
O02691, HCD2_BOVIN;  O18404, HCD2_DROME;  Q99714, HCD2_HUMAN;  
O08756, HCD2_MOUSE;  O70351, HCD2_RAT;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
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