ID   1.1.1.188
DE   Prostaglandin-F synthase.
AN   PGD(2) 11-ketoreductase.
AN   PGF synthetase.
AN   Prostaglandin 11-ketoreductase.
AN   Prostaglandin-D(2) 11-ketoreductase.
AN   Prostaglandin-D(2) 11-reductase.
AN   Prostaglandin-D(2) ketoreductase.
AN   Prostaglandin-F synthetase.
CA   (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate +
CA   NADP(+) = (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate
CA   + NADPH.
CC   -!- Reduces prostaglandin D(2) and prostaglandin H(2) to prostaglandin
CC       F(2); prostaglandin D(2) is not an intermediate in the reduction of
CC       prostaglandin H(2).
CC   -!- Also catalyzes the reduction of a number of carbonyl compounds, such
CC       as 9,10-phenanthroquinone and 4-nitroacetophenone.
PR   PROSITE; PDOC00061;
DR   P42330, AK1C3_HUMAN;  Q5R7C9, AK1C3_PONAB;  P05980, PGFS1_BOVIN;
DR   P52897, PGFS2_BOVIN;
//