ENZYME entry: EC 1.1.1.205

Accepted Name
IMP dehydrogenase.
Alternative Name(s)
IMP oxidoreductase.
Inosinate dehydrogenase.
Inosine 5'-monophosphate dehydrogenase.
Inosine monophosphate oxidoreductase.
Inosinic acid dehydrogenase.
Reaction catalysed
Inosine 5'-phosphate + NAD(+) + H(2)O <=> xanthosine 5'-phosphate + NADH
Comment(s)
  • The enzyme acts on the hydroxy group of the hydrated derivative of the substrate.
  • Formerly EC 1.2.1.14.
Cross-references
PROSITEPDOC00391
BRENDA1.1.1.205
EC2PDB1.1.1.205
ExplorEnz1.1.1.205
PRIAM enzyme-specific profiles1.1.1.205
KEGG Ligand Database for Enzyme Nomenclature1.1.1.205
IUBMB Enzyme Nomenclature1.1.1.205
IntEnz1.1.1.205
MEDLINEFind literature relating to 1.1.1.205
MetaCyc1.1.1.205
UniProtKB/Swiss-Prot
P47996, IMDH1_ARATH;  A0JNA3, IMDH1_BOVIN;  Q6GMG5, IMDH1_DANRE;  
P20839, IMDH1_HUMAN;  P50096, IMDH1_MOUSE;  D3ZLZ7, IMDH1_RAT;  
F6S675, IMDH1_XENTR;  P39567, IMDH1_YEAST;  Q9SA34, IMDH2_ARATH;  
Q3SWY3, IMDH2_BOVIN;  P12269, IMDH2_CRIGR;  B0UXP9, IMDH2_DANRE;  
P12268, IMDH2_HUMAN;  P24547, IMDH2_MOUSE;  E9PU28, IMDH2_RAT;  
F7CYY5, IMDH2_XENTR;  P38697, IMDH2_YEAST;  Q5RGV1, IMDH3_DANRE;  
P50095, IMDH3_YEAST;  P50094, IMDH4_YEAST;  P31002, IMDH_ACICA;  
O67820, IMDH_AQUAE;  Q4WHZ9, IMDH_ASPFU;  Q9KGN8, IMDH_BACHD;  
P21879, IMDH_BACSU;  Q8G3N6, IMDH_BIFLO;  P49058, IMDH_BORBU;  
Q9GZH3, IMDH_CAEEL;  Q59Q46, IMDH_CANAL;  O00086, IMDH_CANAX;  
O50316, IMDH_CHLP8;  Q8KCW4, IMDH_CHLTE;  Q5KP44, IMDH_CRYNJ;  
Q8T6T2, IMDH_CRYPV;  Q54QQ0, IMDH_DICDI;  Q07152, IMDH_DROME;  
P0ADG8, IMDH_ECO57;  P0ADG7, IMDH_ECOLI;  P44334, IMDH_HAEIN;  
Q9HQU4, IMDH_HALSA;  Q9ZL14, IMDH_HELPJ;  P56088, IMDH_HELPY;  
B1L5U5, IMDH_KORCO;  P21620, IMDH_LEIDO;  Q8F4Q4, IMDH_LEPIN;  
Q59011, IMDH_METJA;  P65168, IMDH_MYCBO;  Q49729, IMDH_MYCLE;  
P65167, IMDH_MYCTU;  Q7SFX7, IMDH_NEUCR;  A9A5Y7, IMDH_NITMS;  
Q9L6B7, IMDH_PASMU;  Q12658, IMDH_PNECA;  Q9UY49, IMDH_PYRAB;  
P42851, IMDH_PYRFU;  O58045, IMDH_PYRHO;  Q9KH33, IMDH_RHITR;  
Q7UJL3, IMDH_RHOBA;  O14344, IMDH_SCHPO;  P0ADG9, IMDH_SHIFL;  
Q2FJM6, IMDH_STAA3;  Q2G0Y7, IMDH_STAA8;  Q2YVL6, IMDH_STAAB;  
Q5HIQ7, IMDH_STAAC;  P65169, IMDH_STAAM;  P99106, IMDH_STAAN;  
Q6GJQ7, IMDH_STAAR;  Q6GC82, IMDH_STAAS;  Q8NY70, IMDH_STAAW;  
Q5HRX2, IMDH_STAEQ;  Q8CMQ7, IMDH_STAES;  Q4L385, IMDH_STAHJ;  
Q49UU8, IMDH_STAS1;  P0C0H7, IMDH_STRP1;  P0DB88, IMDH_STRP3;  
Q5X9A3, IMDH_STRP6;  P68839, IMDH_STRP8;  P0DB89, IMDH_STRPQ;  
P0C0H6, IMDH_STRPY;  Q9HLK8, IMDH_THEAC;  Q4VRV8, IMDH_TOXGO;  
P50097, IMDH_TRIFO;  P50098, IMDH_TRYBB;  Q84XA3, IMDH_VIGUN;  
Q0WD32, IMDH_YERPE;  

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