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ENZYME

ENZYME entry: EC 1.1.1.21

Accepted Name
aldose reductase
Alternative Name(s)
aldehyde reductase
polyol dehydrogenase (NADP(+))
Reaction catalysed
  • an alditol + NAD(+) <=> an aldose + H(+) + NADH
  • an alditol + NADP(+) <=> an aldose + H(+) + NADPH
Comment(s)
  • Wide specificity.
  • Formerly EC 1.1.1.139.
Cross-references
BRENDA1.1.1.21
EC2PDB1.1.1.21
ExplorEnz1.1.1.21
PRIAM enzyme-specific profiles1.1.1.21
KEGG Ligand Database for Enzyme Nomenclature1.1.1.21
IUBMB Enzyme Nomenclature1.1.1.21
IntEnz1.1.1.21
MEDLINEFind literature relating to 1.1.1.21
MetaCyc1.1.1.21
Rhea expert-curated reactions1.1.1.21
UniProtKB/Swiss-Prot
P21300, ALD1_MOUSEQ5RJP0, ALD1_RATO08782, ALD2_CRIGR
P45377, ALD2_MOUSEP16116, ALDR_BOVINQ8SSK6, ALDR_ENCCU
P23901, ALDR_HORVUP15121, ALDR_HUMANP45376, ALDR_MOUSE
P80276, ALDR_PIGP15122, ALDR_RABITP07943, ALDR_RAT
Q6IMN8, ALRA_DICDIQ54NZ7, ALRB_DICDIQ55FL3, ALRC_DICDI
P38715, GRE3_YEAST

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
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