ENZYME entry: EC 1.1.1.231

Accepted Name
15-hydroxyprostaglandin-I dehydrogenase (NADP(+)).
Alternative Name(s)
PG I2 dehydrogenase.
Prostacyclin dehydrogenase.
Reaction catalysed
(5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate + NADP(+) <=> (5Z,13E)-6,9-alpha-epoxy-11-alpha-hydroxy-15-oxoprosta-5,13-dienoate + NADPH
Comment(s)
Specific for prostaglandin I(2).
Cross-references
BRENDA1.1.1.231
EC2PDB1.1.1.231
ExplorEnz1.1.1.231
PRIAM enzyme-specific profiles1.1.1.231
KEGG Ligand Database for Enzyme Nomenclature1.1.1.231
IUBMB Enzyme Nomenclature1.1.1.231
IntEnz1.1.1.231
MEDLINEFind literature relating to 1.1.1.231
MetaCyc1.1.1.231

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