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ENZYME

ENZYME entry: EC 1.1.1.237

Accepted Name
hydroxyphenylpyruvate reductase
Reaction catalysed
  • (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NADP(+) <=> 3-(4-hydroxyphenyl)pyruvate + H(+) + NADPH
  • (2R)-2-hydroxy-3-(4-hydroxyphenyl)propanoate + NAD(+) <=> 3-(4-hydroxyphenyl)pyruvate + H(+) + NADH
  • (2R)-3-(3,4-dihydroxyphenyl)lactate + NAD(+) <=> 3-(3,4-dihydroxyphenyl)pyruvate + H(+) + NADH
  • (2R)-3-(3,4-dihydroxyphenyl)lactate + NADP(+) <=> 3-(3,4-dihydroxyphenyl)pyruvate + H(+) + NADPH
Comment(s)
  • The enzyme participates in the biosynthesis of rosmarinic acid.
  • It belongs to the family of D-isomer-specific 2-hydroxyacid dehydrogenases, and prefers NADPH to NADH.
Cross-references
BRENDA1.1.1.237
EC2PDB1.1.1.237
ExplorEnz1.1.1.237
PRIAM enzyme-specific profiles1.1.1.237
KEGG Ligand Database for Enzyme Nomenclature1.1.1.237
IUBMB Enzyme Nomenclature1.1.1.237
IntEnz1.1.1.237
MEDLINEFind literature relating to 1.1.1.237
MetaCyc1.1.1.237
Rhea expert-curated reactions1.1.1.237
UniProtKB/Swiss-Prot
P58409, HCXB_ECO57P30178, HCXB_ECOLIQ65CJ7, HPPR_PLESU

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