ID 1.1.1.238 DE 12beta-hydroxysteroid dehydrogenase. CA 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+) = CA 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH. CC -!- Acts on a number of bile acids, both in their free and conjugated CC forms. //