ENZYME entry: EC 1.1.1.262

Accepted Name
4-hydroxythreonine-4-phosphate dehydrogenase.
Alternative Name(s)
4-(phosphohydroxy)-L-threonine dehydrogenase.
L-threonine 4-phosphate dehydrogenase.
NAD(+)-dependent threonine 4-phosphate dehydrogenase.
Reaction catalysed
4-phosphonooxy-L-threonine + NAD(+) <=> 3-amino-2-oxopropyl phosphate + CO(2) + NADH
Comment(s)
  • The product of the reaction undergoes decarboxylation to give 3-amino-2-oxopropyl phosphate.
  • The enzyme is part of the biosynthesis pathway of the coenzyme pyridoxal 5'-phosphate found in anaerobic bacteria.
Cross-references
BRENDA1.1.1.262
EC2PDB1.1.1.262
ExplorEnz1.1.1.262
PRIAM enzyme-specific profiles1.1.1.262
KEGG Ligand Database for Enzyme Nomenclature1.1.1.262
IUBMB Enzyme Nomenclature1.1.1.262
IntEnz1.1.1.262
MEDLINEFind literature relating to 1.1.1.262
MetaCyc1.1.1.262
UniProtKB/Swiss-Prot
O85987, PDXAL_NOVAR;  Q9CKG8, PDXAL_PASMU;  Q9I1Q5, PDXAL_PSEAE;  
Q92TP3, PDXAL_RHIME;  B7J3R1, PDXA_ACIF2;  B5EL82, PDXA_ACIF5;  
Q8UGD4, PDXA_AGRFC;  O67019, PDXA_AQUAE;  Q5P7J0, PDXA_AROAE;  
A1K9J6, PDXA_AZOSB;  Q89ZK3, PDXA_BACTN;  B2IDU5, PDXA_BEII9;  
Q89MT9, PDXA_BRADU;  P65680, PDXA_BRUME;  P65681, PDXA_BRUSU;  
A4JHP8, PDXA_BURVG;  A0RNS3, PDXA_CAMFF;  A8FMU4, PDXA_CAMJ8;  
Q9PN58, PDXA_CAMJE;  A1W0M2, PDXA_CAMJJ;  Q5HTM4, PDXA_CAMJR;  
Q9A7N4, PDXA_CAUCR;  Q7NQA9, PDXA_CHRVO;  A8ALP8, PDXA_CITK8;  
Q47VJ9, PDXA_COLP3;  Q475Q2, PDXA_CUPNJ;  B7KAA8, PDXA_CYAP7;  
B8FEI1, PDXA_DESAA;  C0QBU5, PDXA_DESAH;  A8ZUN0, PDXA_DESOH;  
A7ZHE5, PDXA_ECO24;  B7L4H5, PDXA_ECO55;  P58713, PDXA_ECO57;  
B5YZ90, PDXA_ECO5E;  B7NHF8, PDXA_ECO7I;  B7MNR1, PDXA_ECO81;  
B7M0E9, PDXA_ECO8A;  C4ZPX8, PDXA_ECOBW;  B1XC53, PDXA_ECODH;  
A7ZW04, PDXA_ECOHS;  Q8FL95, PDXA_ECOL6;  B1IRC4, PDXA_ECOLC;  
P19624, PDXA_ECOLI;  B7N7S7, PDXA_ECOLU;  B6HZ33, PDXA_ECOSE;  
B1LFY8, PDXA_ECOSM;  A4W6F8, PDXA_ENT38;  Q47824, PDXA_ENTAG;  
B2VGP9, PDXA_ERWT9;  Q2N8X0, PDXA_ERYLH;  B7LVS5, PDXA_ESCF3;  
B3E252, PDXA_GEOLS;  Q39Q58, PDXA_GEOMG;  Q5FNS3, PDXA_GLUOX;  
Q17ZN0, PDXA_HELAH;  B6JP92, PDXA_HELP2;  B5Z9L3, PDXA_HELPG;  
Q1CR24, PDXA_HELPH;  Q9ZJ28, PDXA_HELPJ;  B2UVZ9, PDXA_HELPS;  
O26103, PDXA_HELPY;  A4G255, PDXA_HERAR;  B4U950, PDXA_HYDS0;  
A6SV12, PDXA_JANMA;  A1U6F9, PDXA_MARHV;  Q0AQC2, PDXA_MARMM;  
B7KYJ1, PDXA_METC4;  Q3V8A3, PDXA_METCA;  A9VXC3, PDXA_METEP;  
B1ZAJ4, PDXA_METPB;  Q9JX42, PDXA_NEIMA;  Q9K1F9, PDXA_NEIMB;  
P58711, PDXA_NOSS1;  A1B0G5, PDXA_PARDP;  C0QTA7, PDXA_PERMH;  
B4S6L0, PDXA_PROA2;  Q15QB2, PDXA_PSEA6;  Q9I5U4, PDXA_PSEAE;  
Q3IFD2, PDXA_PSEHT;  A4XZJ3, PDXA_PSEMY;  Q88QT5, PDXA_PSEPK;  
Q88A45, PDXA_PSESM;  A4VHI1, PDXA_PSEU5;  P58714, PDXA_RALSO;  
Q984S6, PDXA_RHILO;  Q92QZ0, PDXA_RHIME;  Q7UMZ2, PDXA_RHOBA;  
Q3V7R9, PDXA_RHOPA;  B3Q9S3, PDXA_RHOPT;  Q164G2, PDXA_ROSDO;  
Q1GI38, PDXA_RUEST;  Q21MS9, PDXA_SACD2;  A9MQG1, PDXA_SALAR;  
P58715, PDXA_SALTI;  P58717, PDXA_SALTY;  A8G9P1, PDXA_SERP5;  
Q12K60, PDXA_SHEDO;  Q07YJ9, PDXA_SHEFN;  Q8EB94, PDXA_SHEON;  
B2U260, PDXA_SHIB3;  Q326I1, PDXA_SHIBS;  Q32K42, PDXA_SHIDS;  
Q0T8E3, PDXA_SHIF8;  Q83SQ1, PDXA_SHIFL;  Q3Z5V7, PDXA_SHISS;  
Q2NVX5, PDXA_SODGM;  B4SK42, PDXA_STRM5;  B2FPG6, PDXA_STRMK;  
Q30S58, PDXA_SULDN;  B2V9E6, PDXA_SULSY;  A0LIN6, PDXA_SYNFM;  
Q2JSC8, PDXA_SYNJA;  Q2JKQ8, PDXA_SYNJB;  A5GPX7, PDXA_SYNR3;  
Q55982, PDXA_SYNY3;  Q8DHB4, PDXA_THEEB;  B8GMX6, PDXA_THISH;  
Q9KUS1, PDXA_VIBCH;  Q87ST5, PDXA_VIBPA;  Q8DED3, PDXA_VIBVU;  
Q7MP85, PDXA_VIBVY;  Q8D3I2, PDXA_WIGBR;  Q8PP24, PDXA_XANAC;  
Q4UR40, PDXA_XANC8;  B0RUI2, PDXA_XANCB;  Q8PCE2, PDXA_XANCP;  
B2SPT4, PDXA_XANOP;  A7IJ81, PDXA_XANP2;  Q9PF39, PDXA_XYLFA;  
Q87AJ1, PDXA_XYLFT;  A1JJF5, PDXA_YERE8;  A7FMC0, PDXA_YERP3;  
B2K488, PDXA_YERPB;  P58719, PDXA_YERPE;  A9QZY9, PDXA_YERPG;  
Q3V7Q4, PDXA_YERPS;  B1JKY2, PDXA_YERPY;  Q5NMX3, PDXA_ZYMMO;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
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