ID 1.1.1.269 DE 2-(S)-hydroxypropyl-CoM dehydrogenase. AN 2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase. CA (S)-2-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + CA NADH. CC -!- Highly specific for (S)-2-hydroxyalkyl thioethers of CoM, in contrast CC to EC 1.1.1.268, which is highly specific for the (R)-enantiomer. CC -!- Forms component IV of a four-component enzyme system (comprising CC EC 4.4.1.23 (component I), EC 1.8.1.5 (component II), EC 1.1.1.268 CC (component III) and EC 1.1.1.269 (component IV)) that is involved in CC epoxyalkane carboxylation in Xanthobacter sp. strain Py2. DR Q56841, HCDS1_XANP2; A7IQH5, HCDS3_XANP2; //