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ENZYME entry: EC 1.1.1.281

Accepted Name
GDP-4-dehydro-6-deoxy-D-mannose reductase.
Alternative Name(s)
GDP-4-keto-6-deoxy-D-mannose reductase.
GDP-6-deoxy-D-lyxo-4-hexulose reductase.
Reaction catalysed
GDP-alpha-D-rhamnose + NAD(P)(+) <=> GDP-4-dehydro-alpha-D-rhamnose + NAD(P)H
Comment(s)
  • Differs from EC 1.1.1.187 in that the only product formed is GDP- alpha-D-rhamnose (GDP-6-deoxy-alpha-D-mannose).
  • D-rhamnose is a constituent of lipopolysaccharides of Gram-negative plant and human pathogenic bacteria.
Cross-references
BRENDA1.1.1.281
EC2PDB1.1.1.281
ExplorEnz1.1.1.281
PRIAM enzyme-specific profiles1.1.1.281
KEGG Ligand Database for Enzyme Nomenclature1.1.1.281
IUBMB Enzyme Nomenclature1.1.1.281
IntEnz1.1.1.281
MEDLINEFind literature relating to 1.1.1.281
MetaCyc1.1.1.281
UniProtKB/Swiss-Prot
Q6T1X6, RMD_ANETH;  Q9HTB6, RMD_PSEAE;  

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