ID   1.1.1.283
DE   methylglyoxal reductase (NADPH).
AN   lactaldehyde dehydrogenase (NADP(+)).
AN   methylglyoxal reductase (NADPH-dependent).
CA   (S)-lactaldehyde + NADP(+) = H(+) + methylglyoxal + NADPH.
CC   -!- The enzyme from the yeast Saccharomyces cerevisiae catalyzes the
CC       reduction of a keto group in a number of compounds, forming
CC       enantiopure products.
CC   -!- Among the substrates are methylglyoxal (which is reduced to (S)-
CC       lactaldehyde), 3-methylbutanal, hexane-2,5-dione and 3-chloro-1-
CC       phenylpropan-1-one.
CC   -!- The enzyme differs from EC 1.1.1.78 which is found in mammals, by its
CC       cosubstrate requirement, reaction direction, and enantiomeric
CC       preference.
DR   Q12068, GRE2_YEAST ;  P83775, GRP2_CANAL ;  O32210, GR_BACSU   ;
//