ID   1.1.1.284
DE   S-(hydroxymethyl)glutathione dehydrogenase.
AN   ADH3.
AN   chi-ADH.
AN   class III alcohol dehydrogenase.
AN   FDH.
AN   formaldehyde dehydrogenase.
AN   formaldehyde dehydrogenase (glutathione).
AN   formic dehydrogenase.
AN   GD-FALDH.
AN   glutathione-dependent formaldehyde dehydrogenase.
AN   GS-FDH.
AN   NAD- and glutathione-dependent formaldehyde dehydrogenase.
AN   NAD-dependent formaldehyde dehydrogenase.
AN   NAD-linked formaldehyde dehydrogenase.
CA   (1) NADP(+) + S-(hydroxymethyl)glutathione = H(+) + NADPH +
CA   S-formylglutathione.
CA   (2) NAD(+) + S-(hydroxymethyl)glutathione = H(+) + NADH +
CA   S-formylglutathione.
CC   -!- The substrate, S-(hydroxymethyl)glutathione, forms spontaneously from
CC       glutathione and formaldehyde; its rate of formation is increased in
CC       some bacteria by the presence of EC 4.4.1.22.
CC   -!- Forms part of the pathway that detoxifies formaldehyde, since the
CC       product is hydrolyzed by EC 3.1.2.12.
CC   -!- Also specifically reduces S-nitrosylglutathione.
CC   -!- Formerly EC 1.2.1.1.
DR   P81600, ADHH_GADMO ;  P72324, ADHI_CERS4 ;  P81601, ADHL_GADMO ;
DR   Q96533, ADHX_ARATH ;  Q3ZC42, ADHX_BOVIN ;  Q17335, ADHX_CAEEL ;
DR   Q54TC2, ADHX_DICDI ;  P46415, ADHX_DROME ;  P19854, ADHX_HORSE ;
DR   P11766, ADHX_HUMAN ;  P93629, ADHX_MAIZE ;  P28474, ADHX_MOUSE ;
DR   P80360, ADHX_MYXGL ;  P81431, ADHX_OCTVU ;  A2XAZ3, ADHX_ORYSI ;
DR   Q0DWH1, ADHX_ORYSJ ;  P80572, ADHX_PEA   ;  O19053, ADHX_RABIT ;
DR   P12711, ADHX_RAT   ;  P80467, ADHX_SAAHA ;  P86884, ADHX_SCYCA ;
DR   P79896, ADHX_SPAAU ;  P78870, FADH1_SCHPO;  O74540, FADH2_SCHPO;
DR   P0CL53, FADH_ASPOR ;  Q06099, FADH_CANMA ;  P47734, FADH_METMR ;
DR   P45382, FADH_PARDE ;  O74685, FADH_PICPA ;  P32771, FADH_YEAST ;
DR   A7ZIA4, FRMA_ECO24 ;  Q8X5J4, FRMA_ECO57 ;  A7ZX04, FRMA_ECOHS ;
DR   A1A835, FRMA_ECOK1 ;  Q0TKS7, FRMA_ECOL5 ;  Q8FKG1, FRMA_ECOL6 ;
DR   B1J085, FRMA_ECOLC ;  P25437, FRMA_ECOLI ;  B1LIP1, FRMA_ECOSM ;
DR   Q1RFI7, FRMA_ECOUT ;  P44557, FRMA_HAEIN ;  P39450, FRMA_PHODP ;
DR   Q3Z550, FRMA_SHISS ;  P73138, FRMA_SYNY3 ;
//