ENZYME entry: EC 220.127.116.112
View entry in original ENZYME format
View entry in raw text format (no links)
in this entry
|2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase.
|4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) <=> 2-oxo-2H-pyran-4,6-dicarboxylate + NADPH|
- The enzyme does not act on unsubstituted aliphatic or aromatic
aldehydes or glucose; NAD(+) can replace NADP(+), but with lower
- The enzyme was initially believed to act on 4-carboxy-2-hydroxy-
cis,cis-muconate 6-semialdehyde and produce 4-carboxy-2-hydroxy-
- However, later studies showed that the substrate is the hemiacetal
form, and the product is 2-oxo-2H-pyran-4,6-dicarboxylate.
- Formerly EC 18.104.22.168.
|PRIAM enzyme-specific profiles||22.214.171.1242|
|KEGG Ligand Database for Enzyme Nomenclature||126.96.36.1992|
|IUBMB Enzyme Nomenclature||188.8.131.522|
|MEDLINE||Find literature relating to 184.108.40.2062|
, with possibility to download in different formats, align etc.
entries corresponding to 1.1.1.-
entries corresponding to 1.1.-.-
entries corresponding to 1.-.-.-