ENZYME entry: EC 1.1.1.313

Accepted Name
Sulfoacetaldehyde reductase.
Reaction catalysed
Isethionate + NADP(+) <=> 2-sulfoacetaldehyde + NADPH
Comment(s)
  • Catalyzes the reaction only in the opposite direction.
  • Involved in taurine degradation.
  • The bacterium Chromohalobacter salexigens strain DSM 3043 possesses two enzymes that catalyze this reaction, a constitutive enzyme (encoded by isfD2) and an inducible enzyme (encoded by isfD).
  • The latter is induced by taurine, and is responsible for most of the activity observed in taurine-grown cells.
Cross-references
BRENDA1.1.1.313
EC2PDB1.1.1.313
ExplorEnz1.1.1.313
PRIAM enzyme-specific profiles1.1.1.313
KEGG Ligand Database for Enzyme Nomenclature1.1.1.313
IUBMB Enzyme Nomenclature1.1.1.313
IntEnz1.1.1.313
MEDLINEFind literature relating to 1.1.1.313
MetaCyc1.1.1.313
UniProtKB/Swiss-Prot
Q1QU27, ISFD2_CHRSD;  Q1R183, ISFD_CHRSD;  D3U1D9, ISFD_KLEOX;  

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