ENZYME entry: EC 1.1.1.315
| Accepted Name |
|---|
| 11-cis-retinol dehydrogenase.
|
| Reaction catalysed |
|---|
| 11-cis-retinol-[retinal-binding-protein] + NAD(+) <=> 11-cis-retinal-[retinol-binding-protein] + NADH |
| Comment(s) |
|---|
- This enzyme, abundant in the retinal pigment epithelium, catalyzes
the reduction of 11-cis-retinol to 11-cis-retinal while the substrate
is bound to the retinal-binding protein.
- This is a crucial step in the regeneration of 11-cis-retinal,
the chromophore of rhodopsin.
- The enzyme can also accept other cis forms of retinol.
|
| Cross-references |
|---|
| BRENDA | 1.1.1.315 |
| EC2PDB | 1.1.1.315 |
| ExplorEnz | 1.1.1.315 |
| PRIAM enzyme-specific profiles | 1.1.1.315 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.315 |
| IUBMB Enzyme Nomenclature | 1.1.1.315 |
| IntEnz | 1.1.1.315 |
| MEDLINE | Find literature relating to 1.1.1.315 |
| MetaCyc | 1.1.1.315 |
| UniProtKB/Swiss-Prot |
|
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