ID   1.1.1.334
DE   methylecgonone reductase.
CA   ecgonine methyl ester + NADP(+) = ecgonone methyl ester + H(+) + NADPH.
CC   -!- The enzyme from the plant Erythroxylum coca catalyzes the penultimate
CC       step in the biosynthesis of cocaine.
CC   -!- In vivo the reaction proceeds in the opposite direction.
CC   -!- With NADH instead of NADPH the reaction rate is reduced to 14%.
CC   -!- The enzyme also reduces tropinone, nortropinone and
CC       6-hydroxytropinone but with lower reaction rates.
DR   E7C196, MER_ERYCB  ;
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