To improve security and privacy, we are moving our web pages and services from HTTP to HTTPS.
To give users of web services time to transition to HTTPS, we will support separate HTTP and HTTPS services until the end of 2017.
From January 2018 most HTTP traffic will be automatically redirected to HTTPS. [more...]
View this page in https

ENZYME entry: EC 1.1.1.337

Accepted Name
L-2-hydroxycarboxylate dehydrogenase (NAD(+)).
Alternative Name(s)
(R)-sulfolactate dehydrogenase.
L-2-hydroxyacid dehydrogenase (NAD(+)).
L-sulfolactate dehydrogenase.
Reaction catalysed
A (2S)-2-hydroxycarboxylate + NAD(+) <=> a 2-oxocarboxylate + NADH
Comment(s)
  • The enzyme from the archaeon Methanocaldococcus jannaschii acts on multiple L-2-hydroxycarboxylates including (2R)-3-sulfolactate, (S)- malate, (S)-lactate, and (S)-2-hydroxyglutarate.
  • Note that (2R)-3-sulfolactate has the same stereo configuration as (2S)-2-hydroxycarboxylates.
Cross-references
BRENDA1.1.1.337
EC2PDB1.1.1.337
ExplorEnz1.1.1.337
PRIAM enzyme-specific profiles1.1.1.337
KEGG Ligand Database for Enzyme Nomenclature1.1.1.337
IUBMB Enzyme Nomenclature1.1.1.337
IntEnz1.1.1.337
MEDLINEFind literature relating to 1.1.1.337
MetaCyc1.1.1.337
UniProtKB/Swiss-Prot
Q58820, COMC_METJA;  O27273, COMC_METTH;  

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-