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ENZYME entry: EC

Accepted Name
L-2-hydroxycarboxylate dehydrogenase (NAD(+)).
Alternative Name(s)
(R)-sulfolactate dehydrogenase.
L-2-hydroxyacid dehydrogenase (NAD(+)).
L-sulfolactate dehydrogenase.
Reaction catalysed
A (2S)-2-hydroxycarboxylate + NAD(+) <=> a 2-oxocarboxylate + NADH
  • The enzyme from the archaeon Methanocaldococcus jannaschii acts on multiple L-2-hydroxycarboxylates including (2R)-3-sulfolactate, (S)- malate, (S)-lactate, and (S)-2-hydroxyglutarate.
  • Note that (2R)-3-sulfolactate has the same stereo configuration as (2S)-2-hydroxycarboxylates.
PRIAM enzyme-specific profiles1.1.1.337
KEGG Ligand Database for Enzyme Nomenclature1.1.1.337
IUBMB Enzyme Nomenclature1.1.1.337
MEDLINEFind literature relating to
Q58820, COMC_METJA;  O27273, COMC_METTH;  

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