ID   1.1.1.34
DE   Hydroxymethylglutaryl-CoA reductase (NADPH).
AN   3-hydroxy-3-methylglutaryl-coenzyme A reductase.
AN   HMG-CoA reductase.
CA   (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA +
CA   2 NADPH.
CC   -!- The enzyme is inactivated by EC 2.7.11.31 and reactivated by
CC       EC 3.1.3.47.
PR   PROSITE; PDOC00064;
DR   P14891, HMDH1_ARATH;  P34135, HMDH1_DICDI;  O64966, HMDH1_GOSHI;
DR   P29057, HMDH1_HEVBR;  A2X8W3, HMDH1_ORYSI;  Q0DY59, HMDH1_ORYSJ;
DR   P48020, HMDH1_SOLTU;  P12683, HMDH1_YEAST;  P43256, HMDH2_ARATH;
DR   Q9XEL8, HMDH2_CAPAN;  P34136, HMDH2_DICDI;  O64967, HMDH2_GOSHI;
DR   P29058, HMDH2_HEVBR;  P48022, HMDH2_SOLLC;  Q41437, HMDH2_SOLTU;
DR   P12684, HMDH2_YEAST;  Q00583, HMDH3_HEVBR;  Q9XHL5, HMDH3_ORYSJ;
DR   Q41438, HMDH3_SOLTU;  Q9YAS4, HMDH_AERPE ;  O76819, HMDH_AGRIP ;
DR   O28538, HMDH_ARCFU ;  Q9Y7D2, HMDH_ASPTE ;  Q0C8L9, HMDH_ASPTN ;
DR   P54960, HMDH_BLAGE ;  P48021, HMDH_CAMAC ;  Q03163, HMDH_CATRO ;
DR   P00347, HMDH_CRIGR ;  O74164, HMDH_CYBJA ;  P14773, HMDH_DROME ;
DR   Q12577, HMDH_GIBFU ;  Q59468, HMDH_HALVD ;  P04035, HMDH_HUMAN ;
DR   O24594, HMDH_MAIZE ;  P09610, HMDH_MESAU ;  Q58116, HMDH_METJA ;
DR   O26662, HMDH_METTH ;  Q01237, HMDH_MOUSE ;  Q01559, HMDH_NICSY ;
DR   Q12649, HMDH_PHYBL ;  Q1W675, HMDH_PIG   ;  Q5R6N3, HMDH_PONAB ;
DR   Q9V1R3, HMDH_PYRAB ;  O59469, HMDH_PYRHO ;  Q29512, HMDH_RABIT ;
DR   P51639, HMDH_RAT   ;  P16237, HMDH_SCHMA ;  Q10283, HMDH_SCHPO ;
DR   P16393, HMDH_STRPU ;  O08424, HMDH_SULSO ;  P20715, HMDH_XENLA ;
//