ID   1.1.1.351
DE   phosphogluconate dehydrogenase [NAD(P)(+)-dependent, decarboxylating].
CA   (1) 6-phospho-D-gluconate + NAD(+) = CO2 + D-ribulose 5-phosphate + NADH.
CA   (2) 6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate +
CA   NADPH.
CC   -!- The enzyme participates in the oxidative branch of the pentose
CC       phosphate pathway, whose main purpose is to produce reducing power
CC       and pentose for biosynthetic reactions.
CC   -!- Unlike EC 1.1.1.44, it is not specific for NADP(+) and can accept
CC       both cofactors with similar efficiency. cf. EC 1.1.1.343.
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