ENZYME entry: EC 1.1.1.352

Accepted Name
5'-hydroxyaverantin dehydrogenase.
Alternative Name(s)
HAVN dehydrogenase.
Reaction catalysed
  • (1'S,5'S)-hydroxyaverantin + NAD(+) <=> 5'-oxoaverantin + NADH
  • (1'S,5'R)-hydroxyaverantin + NAD(+) <=> 5'-oxoaverantin + NADH
Comment(s)
  • Isolated from the aflatoxin-producing mold Aspergillus parasiticus.
  • Involved in aflatoxin biosynthesis.
  • 5'-oxoaverantin will spontaneously form averufin by intramolecular ketalisation.
  • Cf. EC 4.2.1.142.
Cross-references
BRENDA1.1.1.352
EC2PDB1.1.1.352
ExplorEnz1.1.1.352
PRIAM enzyme-specific profiles1.1.1.352
KEGG Ligand Database for Enzyme Nomenclature1.1.1.352
IUBMB Enzyme Nomenclature1.1.1.352
IntEnz1.1.1.352
MEDLINEFind literature relating to 1.1.1.352
MetaCyc1.1.1.352
UniProtKB/Swiss-Prot
P87017, AFLH_ASPPU

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