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ENZYME entry: EC

Accepted Name
Aklaviketone reductase.
Reaction catalysed
Aklavinone + NADP(+) <=> aklaviketone + NADPH
  • The enzyme is involved in the synthesis of the aklavinone aglycone, a common precursor for several anthracycline antibiotics including aclacinomycins, daunorubicin and doxorubicin.
  • The enzyme from the Gram-negative bacterium Streptomyces sp. C5 produces daunomycin.
PRIAM enzyme-specific profiles1.1.1.362
KEGG Ligand Database for Enzyme Nomenclature1.1.1.362
IUBMB Enzyme Nomenclature1.1.1.362
MEDLINEFind literature relating to
Q53882, DNRE_STRS5

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