ID 1.1.1.381 DE 3-hydroxy acid dehydrogenase. CA L-allo-threonine + NADP(+) = aminoacetone + CO2 + NADPH. CC -!- The enzyme, purified from the bacterium Escherichia coli and the CC yeast Saccharomyces cerevisiae, shows activity with a range of 3- and CC 4-carbon 3-hydroxy acids. CC -!- The highest activity is seen with L-allo-threonine and D-threonine. CC -!- The enzyme from E. coli also shows high activity with L-serine, CC D-serine, (S)-3-hydroxy-2-methylpropanoate and (R)-3-hydroxy-2- CC methylpropanoate. CC -!- The enzyme has no activity with NAD(+) or L-threonine (cf. CC EC 1.1.1.103). DR Q8X505, YDFG_ECO57 ; Q8FHD2, YDFG_ECOL6 ; P39831, YDFG_ECOLI ; DR P69935, YDFG_SALTI ; P69936, YDFG_SALTY ; Q83RE8, YDFG_SHIFL ; DR Q9P7B4, YI13_SCHPO ; Q05016, YM71_YEAST ; //