ENZYME entry: EC 1.1.1.40
| Accepted Name |
|---|
| Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
|
| Alternative Name(s) |
|---|
| Malic enzyme. |
| NADP-malic enzyme. |
| Pyruvic-malic carboxylase. |
| Reaction catalysed |
|---|
- (S)-malate + NADP(+) <=> pyruvate + CO(2) + NADPH
- Oxaloacetate <=> pyruvate + CO(2)
|
| Comment(s) |
|---|
| The enzyme catalyzes the oxidative decarboxylation of (S)-malate in
the presence of NADP(+) and divalent metal ions, and decarboxylation
of oxaloacetate, cf. EC 1.1.1.38 and EC 1.1.1.39.
|
| Cross-references |
|---|
| PROSITE | PDOC00294 |
| BRENDA | 1.1.1.40 |
| EC2PDB | 1.1.1.40 |
| ExplorEnz | 1.1.1.40 |
| PRIAM enzyme-specific profiles | 1.1.1.40 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.40 |
| IUBMB Enzyme Nomenclature | 1.1.1.40 |
| IntEnz | 1.1.1.40 |
| MEDLINE | Find literature relating to 1.1.1.40 |
| MetaCyc | 1.1.1.40 |
| UniProtKB/Swiss-Prot |
| P76558, MAO2_ECOLI; | P43837, MAO2_HAEIN; | O30808, MAO2_RHIME; |
| Q9ZDF6, MAO2_RICPR; | Q9ZFV8, MAO2_SALTY; | P36444, MAOC_FLAPR; |
| P22178, MAOC_FLATR; | P16243, MAOC_MAIZE; | P43279, MAOC_ORYSJ; |
| P37222, MAOC_SOLLC; | P78715, MAOH_NEOFR; | Q16798, MAON_HUMAN; |
| Q8BMF3, MAON_MOUSE; | O82191, MAOP1_ARATH; | Q9LYG3, MAOP2_ARATH; |
| Q9XGZ0, MAOP3_ARATH; | Q9CA83, MAOP4_ARATH; | P28227, MAOX_ANAPL; |
| Q92060, MAOX_CHICK; | P40927, MAOX_COLLI; | Q6TU48, MAOX_DICDI; |
| P48163, MAOX_HUMAN; | P37223, MAOX_MESCR; | P06801, MAOX_MOUSE; |
| P12628, MAOX_PHAVU; | Q29558, MAOX_PIG; | P84539, MAOX_POPEU; |
| P34105, MAOX_POPTR; | P13697, MAOX_RAT; | P51615, MAOX_VITVI; |
|
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