ENZYME entry: EC 1.1.1.413
Accepted Name | ||
---|---|---|
A-factor type gamma-butyrolactone 1'-reductase (1S-forming) | ||
Reaction catalysed | ||
a (3R,4R)-3-[(1S)-1-hydroxyalkyl]-4-(hydroxymethyl)oxolan-2-one + NADP(+) <=> a (3R,4R)-3-alkanoyl-4-(hydroxymethyl)oxolan-2-one + H(+) + NADPH | ||
Comment(s) | ||
The enzyme, which is found in bacteria that produce virginiae- butanolide (VB) type gamma-butyrolactone autoregulators, reduces its substrate stereospecifically, forming a hydroxyl group in the (S) configuration. | ||
Cross-references | ||
BRENDA | 1.1.1.413 | |
EC2PDB | 1.1.1.413 | |
ExplorEnz | 1.1.1.413 | |
PRIAM enzyme-specific profiles | 1.1.1.413 | |
KEGG Ligand Database for Enzyme Nomenclature | 1.1.1.413 | |
IUBMB Enzyme Nomenclature | 1.1.1.413 | |
IntEnz | 1.1.1.413 | |
MEDLINE | Find literature relating to 1.1.1.413 | |
MetaCyc | 1.1.1.413 | |
Rhea expert-curated reactions | 1.1.1.413 | |
UniProtKB/Swiss-Prot |
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