ID   1.1.1.430
DE   D-xylose reductase (NADH).
CA   NAD(+) + xylitol = D-xylose + H(+) + NADH.
CC   -!- Xylose reductases catalyze the reduction of xylose to xylitol,
CC       the initial reaction in the fungal D-xylose degradation pathway.
CC   -!- Most of the enzymes exhibit a strict requirement for NADPH (cf.
CC       EC 1.1.1.431).
CC   -!- Some D-xylose reductases have dual cofactor specificity, though they
CC       still prefer NADPH to NADH (cf. EC 1.1.1.307).
CC   -!- The enzyme from Candida parapsilosis is a rare example of a xylose
CC       reductase that significantly prefers NADH, with Km and Vmax values
CC       for NADH being 10-fold lower and 10-fold higher, respectively, than
CC       for NADPH.
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