ENZYME entry: EC 1.1.1.53

Accepted Name
3-alpha(or 20-beta)-hydroxysteroid dehydrogenase.
Alternative Name(s)
(R)-20-hydroxysteroid dehydrogenase.
Cortisone reductase.
Reaction catalysed
Androstan-3-alpha,17-beta-diol + NAD(+) <=> 17-beta-hydroxyandrostan-3-one + NADH
Comment(s)
The 3-alpha-hydroxy group or 20-beta-hydroxy group of pregnane and androstane steroids can act as donor.
Cross-references
PROSITEPDOC00060
BRENDA1.1.1.53
EC2PDB1.1.1.53
ExplorEnz1.1.1.53
PRIAM enzyme-specific profiles1.1.1.53
KEGG Ligand Database for Enzyme Nomenclature1.1.1.53
IUBMB Enzyme Nomenclature1.1.1.53
IntEnz1.1.1.53
MEDLINEFind literature relating to 1.1.1.53
MetaCyc1.1.1.53
UniProtKB/Swiss-Prot
P69166, HSD_MYCBO;  P9WGT0, HSD_MYCTO;  P9WGT1, HSD_MYCTU;  
P19992, HSD_STREX;  

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