ID 1.1.1.95 DE Phosphoglycerate dehydrogenase. AN 3-phosphoglycerate dehydrogenase. AN 3-phosphoglyceric acid dehydrogenase. AN 3PHP reductase. AN Alpha-KG reductase. AN Alpha-phosphoglycerate dehydrogenase. AN D-3-phosphoglycerate dehydrogenase. AN Glycerate 3-phosphate dehydrogenase. AN Glycerate-1,3-phosphate dehydrogenase. AN PGDH. AN Phosphoglycerate oxidoreductase. AN Phosphoglyceric acid dehydrogenase. CA (1) 3-phospho-D-glycerate + NAD(+) = 3-phosphonooxypyruvate + NADH. CA (2) 2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + NADH. CC -!- Catalyzes the first committed step in the phosphoserine pathway of CC serine biosynthesis in Escherichia coli. CC -!- Reaction (1) occurs predominantly in the reverse direction and is CC inhibited by serine and glycine. CC -!- The enzyme is unusual in that it also acts as a D- and L-2- CC hydroxyglutarate dehydrogenase (with the D-form being the better CC substrate) and as a 2-oxoglutarate reductase. PR PROSITE; PDOC00063; DR P40510, SER33_YEAST; O04130, SERA_ARATH ; O29445, SERA_ARCFU ; DR P35136, SERA_BACSU ; Q5EAD2, SERA_BOVIN ; Q54UH8, SERA_DICDI ; DR P0A9T2, SERA_ECO57 ; P0A9T1, SERA_ECOL6 ; P0A9T0, SERA_ECOLI ; DR P43885, SERA_HAEIN ; O43175, SERA_HUMAN ; Q60HD7, SERA_MACFA ; DR Q58424, SERA_METJA ; O27051, SERA_METTH ; Q61753, SERA_MOUSE ; DR P0A545, SERA_MYCBO ; O33116, SERA_MYCLE ; P0A544, SERA_MYCTU ; DR A5A6P1, SERA_PANTR ; A5GFY8, SERA_PIG ; Q5R7M2, SERA_PONAB ; DR O08651, SERA_RAT ; P87228, SERA_SCHPO ; P0A9T3, SERA_SHIFL ; DR P73821, SERA_SYNY3 ; P40054, SERA_YEAST ; //