ENZYME entry: EC 1.1.1.n6
| Accepted Name |
|---|
| D-chiro-inositol 3-dehydrogenase.
|
| Alternative Name(s) |
|---|
| DCI 3-dehydrogenase. |
| Reaction catalysed |
|---|
| D-chiro-inositol + NAD(+) <=> 2,3,5/4,6-pentahydroxycyclohexanone + NADH |
| Comment(s) |
|---|
- The enzyme also catalyzes the reaction of EC 1.1.1.18 and can also
use D-glucose and D-xylose.
- It shows trace activity with D-ribose and D-fructose.
- Part of the myo-inositol/D-chiro-inositol degradation pathway leading
to acetyl-CoA together EC 5.3.99.n1, EC 4.2.1.44, EC 3.7.1.n2,
EC 5.3.1.n1, EC 2.7.1.92, EC 4.1.2.29 and EC 1.2.1.18.
|
| Cross-references |
|---|
| UniProtKB/Swiss-Prot |
|
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