ENZYME entry: EC 1.1.99.28

Accepted Name
Glucose-fructose oxidoreductase.
Reaction catalysed
D-glucose + D-fructose <=> D-gluconolactone + D-glucitol
Comment(s)
  • D-mannose, D-xylose, D-galactose, 2-deoxy-D-glucose and L-arabinose will function as aldose substrates, but with low affinities.
  • The ketose substrate must be in the open-chain form.
  • The apparent affinity for fructose is low, because little of the fructose substrate is in the open-chain form.
  • Xylulose and glycerone (dihydroxyacetone) will replace fructose, but they are poor substrates.
  • The enzyme from Zymomonas mobilis contains tightly bound NADP(+).
Cross-references
BRENDA1.1.99.28
EC2PDB1.1.99.28
ExplorEnz1.1.99.28
PRIAM enzyme-specific profiles1.1.99.28
KEGG Ligand Database for Enzyme Nomenclature1.1.99.28
IUBMB Enzyme Nomenclature1.1.99.28
IntEnz1.1.99.28
MEDLINEFind literature relating to 1.1.99.28
MetaCyc1.1.99.28
UniProtKB/Swiss-Prot
Q07982, GFO_ZYMMO

View entry in original ENZYME format
View entry in raw text format (no links)

All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.99.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-