ID 1.1.99.30 DE 2-oxo-acid reductase. AN (2R)-hydroxycarboxylate-viologen-oxidoreductase. AN 2-oxoacid reductase. AN HVOR. CA A + a (2R)-2-hydroxycarboxylate = a 2-oxocarboxylate + AH2. CC -!- Has broad substrate specificity, with 2-oxo-monocarboxylates and CC 2-oxo-dicarboxylates acting as substrates. CC -!- Branching in a substrate at the C-3 position results in loss of CC activity. CC -!- The enzyme from Proteus sp. is inactivated by oxygen. DR Q9R4Y1, HVOR_PROVU ; //