ID   1.1.99.36
DE   alcohol dehydrogenase (nicotinoprotein).
AN   NDMA-dependent alcohol dehydrogenase.
AN   nicotinoprotein alcohol dehydrogenase.
CA   A + ethanol = acetaldehyde + AH2.
CC   -!- Nicotinoprotein alcohol dehydrogenases are unique medium-chain
CC       dehydrogenases/reductases (MDR) alcohol dehydrogenases that have a
CC       tightly bound NAD(+)/NADH cofactor that does not dissociate during
CC       the catalytic process.
CC   -!- Instead, the cofactor is regenerated by a second substrate or
CC       electron carrier.
CC   -!- While the in vivo electron acceptor is not known, N,N-dimethyl-4-
CC       nitrosoaniline (NDMA) can serve this function in vitro.
CC   -!- The enzyme from the Gram-positive bacterium Amycolatopsis methanolica
CC       can accept many primary alcohols as substrates, including
CC       benzylalcohol.
DR   P80175, ADHN_AMYME ;  P81747, ADHN_RHOER ;
//