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ENZYME entry: EC

Accepted Name
Ubiquinol oxidase (H(+)-transporting).
Alternative Name(s)
Cytochrome bb3 oxidase.
Cytochrome bd-II oxidase.
Cytochrome bo oxidase.
Reaction catalysed
2 ubiquinol + O(2) + n H(+)(Side 1) <=> 2 ubiquinone + 2 H(2)O + n H(+)(Side 2)
Cu cation; Heme.
  • This terminal oxidase enzyme generates proton motive force by two mechanisms: (1) transmembrane charge separation resulting from utilizing protons and electrons originating from opposite sides of the membrane to generate water, and (2) active pumping of protons across the membrane.
  • The bioenergetic efficiency (the number of charges driven across the membrane per electron used to reduce oxygen to water) depends on the enzyme; for example, for the bo(3) oxidase it is 2, while for the bd-II oxidase it is 1.
  • Cf. EC
PRIAM enzyme-specific profiles1.10.3.10
KEGG Ligand Database for Enzyme Nomenclature1.10.3.10
IUBMB Enzyme Nomenclature1.10.3.10
MEDLINEFind literature relating to
P26458, APPB_ECOLI;  P26459, APPC_ECOLI;  P57543, CYOB_BUCAI;  

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