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ENZYME entry: EC 1.10.3.12

Accepted Name
Menaquinol oxidase (H(+)-transporting).
Alternative Name(s)
Cytochrome aa3-600 oxidase.
Cytochrome bd oxidase.
Reaction catalysed
2 menaquinol + O(2) <=> 2 menaquinone + 2 H(2)O
Cofactor(s)
Cu cation; Heme.
Comment(s)
  • Cytochrome aa3-600, one of the principal respiratory oxidases from Bacillus subtilis, is a member of the heme-copper superfamily of oxygen reductases, and is a close homolog of the cytochrome bo3 ubiquinol oxidase from Escherichia coli, but uses menaquinol instead of ubiquinol as a substrate.
  • The enzyme also pumps protons across the membrane bilayer, generating a proton motive force.
Cross-references
BRENDA1.10.3.12
EC2PDB1.10.3.12
ExplorEnz1.10.3.12
PRIAM enzyme-specific profiles1.10.3.12
KEGG Ligand Database for Enzyme Nomenclature1.10.3.12
IUBMB Enzyme Nomenclature1.10.3.12
IntEnz1.10.3.12
MEDLINEFind literature relating to 1.10.3.12
MetaCyc1.10.3.12

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.10.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.10.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-