ENZYME entry: EC 1.10.3.12

Accepted Name
Menaquinol oxidase (H(+)-transporting).
Alternative Name(s)
Cytochrome aa3-600 oxidase.
Cytochrome bd oxidase.
Reaction catalysed
2 menaquinol + O(2) <=> 2 menaquinone + 2 H(2)O
Cofactor(s)
Cu cation; Heme.
Comment(s)
  • Cytochrome aa3-600, one of the principal respiratory oxidases from Bacillus subtilis, is a member of the heme-copper superfamily of oxygen reductases, and is a close homolog of the cytochrome bo3 ubiquinol oxidase from Escherichia coli, but uses menaquinol instead of ubiquinol as a substrate.
  • The enzyme also pumps protons across the membrane bilayer, generating a proton motive force.
Cross-references
BRENDA1.10.3.12
EC2PDB1.10.3.12
ExplorEnz1.10.3.12
PRIAM enzyme-specific profiles1.10.3.12
KEGG Ligand Database for Enzyme Nomenclature1.10.3.12
IUBMB Enzyme Nomenclature1.10.3.12
IntEnz1.10.3.12
MEDLINEFind literature relating to 1.10.3.12
MetaCyc1.10.3.12

View entry in original ENZYME format
View entry in raw text format (no links)
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.10.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.10.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-