ENZYME entry: EC 1.11.1.17

Accepted Name
Glutathione amide-dependent peroxidase.
Reaction catalysed
2 glutathione amide + H(2)O(2) <=> glutathione amide disulfide + 2 H(2)O
Comment(s)
  • This enzyme, which has been characterized from the proteobacterium Marichromatium gracile, is a chimeric protein, containing a peroxiredoxin-like N-terminus and a glutaredoxin-like C terminus.
  • The enzyme has peroxidase activity toward hydrogen peroxide and several small alkyl hydroperoxides, and is thought to represent an early adaptation for fighting oxidative stress.
  • The glutathione amide disulfide produced by this enzyme can be restored to glutathione amide by EC 1.8.1.16.
Cross-references
BRENDA1.11.1.17
EC2PDB1.11.1.17
ExplorEnz1.11.1.17
PRIAM enzyme-specific profiles1.11.1.17
KEGG Ligand Database for Enzyme Nomenclature1.11.1.17
IUBMB Enzyme Nomenclature1.11.1.17
IntEnz1.11.1.17
MEDLINEFind literature relating to 1.11.1.17
MetaCyc1.11.1.17
UniProtKB/Swiss-Prot
B3EWI1, GSPRX_MARGR

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