ID 1.11.1.20 DE prostamide/prostaglandin F2alpha synthase. AN prostamide/PGF synthase. AN prostamide/prostaglandin F synthase. AN prostamide F synthase. AN TPGF synthase. CA [thioredoxin]-dithiol + prostaglandin H2 = [thioredoxin]-disulfide + CA prostaglandin F2alpha. CC -!- The enzyme contains a thioredoxin-type disulfide as a catalytic CC group. CC -!- Prostamide H2 and prostaglandin H2 are the best substrates; the CC latter is converted to prostaglandin F2alpha. CC -!- The enzyme also reduces tert-butyl hydroperoxide, cumene CC hydroperoxide and H2O2, but not prostaglandin D2 or prostaglandin E2. DR C1C416, PXL2B_AQUCT; Q58CY6, PXL2B_BOVIN; Q6NV24, PXL2B_DANRE; DR Q8TBF2, PXL2B_HUMAN; Q9DB60, PXL2B_MOUSE; A9CQL8, PXL2B_PIG ; DR Q5R7S9, PXL2B_PONAB; D3ZVR7, PXL2B_RAT ; B5X9L9, PXL2B_SALSA; DR Q6AZG8, PXL2B_XENLA; Q28IJ3, PXL2B_XENTR; //