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ENZYME

ENZYME entry: EC 1.12.1.4

Accepted Name
hydrogenase (NAD(+), ferredoxin)
Alternative Name(s)
bifurcating [FeFe] hydrogenase
Reaction catalysed
2 H2 + NAD(+) + 2 oxidized [2Fe-2S]-[ferredoxin] <=> 3 H(+) + NADH + 2 reduced [2Fe-2S]-[ferredoxin]
Comment(s)
  • The enzyme from Thermotoga maritima contains a [FeFe] cluster (H-cluster) and iron-sulfur clusters.
  • It works in the direction evolving hydrogen as a means of eliminating excess reducing equivalents.
Cross-references
BRENDA1.12.1.4
EC2PDB1.12.1.4
ExplorEnz1.12.1.4
PRIAM enzyme-specific profiles1.12.1.4
KEGG Ligand Database for Enzyme Nomenclature1.12.1.4
IUBMB Enzyme Nomenclature1.12.1.4
IntEnz1.12.1.4
MEDLINEFind literature relating to 1.12.1.4
MetaCyc1.12.1.4
Rhea expert-curated reactions1.12.1.4
UniProtKB/Swiss-Prot
O52683, HYDA_THEMAO52682, HYDB_THEMAO52681, HYDC_THEMA

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