ENZYME entry: EC 1.13.11.19

Accepted Name
Cysteamine dioxygenase.
Alternative Name(s)
Cysteamine oxygenase.
Persulfurase.
Reaction catalysed
2-aminoethanethiol + O(2) <=> hypotaurine
Cofactor(s)
Iron.
Comment(s)
  • Involved in the biosynthesis of taurine.
  • Requires catalytic amounts of a cofactor-like compound, such as sulfur, sufide, selenium or methylene blue for maximal activity.
  • 3-aminopropanethiol (homocysteamine) and 2-mercaptoethanol can also act as substrates, but glutathione, cysteine, and cysteine ethyl- and methyl esters are not good substrates.
Cross-references
BRENDA1.13.11.19
EC2PDB1.13.11.19
ExplorEnz1.13.11.19
PRIAM enzyme-specific profiles1.13.11.19
KEGG Ligand Database for Enzyme Nomenclature1.13.11.19
IUBMB Enzyme Nomenclature1.13.11.19
IntEnz1.13.11.19
MEDLINEFind literature relating to 1.13.11.19
MetaCyc1.13.11.19
UniProtKB/Swiss-Prot
Q556I2, AEDO_DICDI;  Q96SZ5, AEDO_HUMAN;  Q6PDY2, AEDO_MOUSE;  

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