ENZYME entry: EC 1.13.11.3

Accepted Name
Protocatechuate 3,4-dioxygenase.
Alternative Name(s)
Protocatechuate oxygenase.
Reaction catalysed
3,4-dihydroxybenzoate + O(2) <=> 3-carboxy-cis,cis-muconate
Cofactor(s)
Fe cation.
Comment(s)
  • The enzyme, which participates in the degradation of aromatic compounds, catalyzes the intradiol addition of both oxygen atoms from molecular oxygen, resulting in ortho-cleavage of the aromatic ring.
  • The type of cleavage leads to mineralization via the intermediate 3-oxoadipate.
  • Formerly EC 1.13.1.3 and EC 1.99.2.3.
Cross-references
PROSITEPDOC00079
BRENDA1.13.11.3
EC2PDB1.13.11.3
ExplorEnz1.13.11.3
PRIAM enzyme-specific profiles1.13.11.3
KEGG Ligand Database for Enzyme Nomenclature1.13.11.3
IUBMB Enzyme Nomenclature1.13.11.3
IntEnz1.13.11.3
MEDLINEFind literature relating to 1.13.11.3
MetaCyc1.13.11.3
UniProtKB/Swiss-Prot
P20371, PCXA_ACIAD;  P15109, PCXA_BURCE;  P00436, PCXA_PSEPU;  
P20372, PCXB_ACIAD;  P15110, PCXB_BURCE;  P00437, PCXB_PSEPU;  

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