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ENZYME

ENZYME entry: EC 1.13.11.58

Accepted Name
linoleate 9S-lipoxygenase
Alternative Name(s)
9-lipoxygenase
9S-lipoxygenase
linoleate 9-lipoxygenase
Reaction catalysed
(9Z,12Z)-octadecadienoate + O2 <=> (9S)-hydroperoxy-(10E,12Z)-octadecadienoate
Comment(s)
  • A common plant lipoxygenase that oxidizes linoleate and alpha- linolenate, the two most common polyunsaturated fatty acids in plants, by inserting molecular oxygen at the C9 position with (S)- configuration.
  • The enzyme plays a physiological role during the early stages of seedling growth.
  • The enzyme from Arabidopsis thaliana shows comparable activity toward linoleate and linolenate.
  • EC 1.13.11.12 catalyzes a similar reaction at another position of these fatty acids.
Cross-references
BRENDA1.13.11.58
EC2PDB1.13.11.58
ExplorEnz1.13.11.58
PRIAM enzyme-specific profiles1.13.11.58
KEGG Ligand Database for Enzyme Nomenclature1.13.11.58
IUBMB Enzyme Nomenclature1.13.11.58
IntEnz1.13.11.58
MEDLINEFind literature relating to 1.13.11.58
MetaCyc1.13.11.58
Rhea expert-curated reactions1.13.11.58
UniProtKB/Swiss-Prot
O35936, ALOX8_MOUSEP37831, LOX11_SOLTUO24379, LOX12_SOLTU
Q43189, LOX13_SOLTUQ43190, LOX14_SOLTUQ43191, LOX15_SOLTU
Q41238, LOX16_SOLTUO22507, LOX17_SOLTUO22508, LOX18_SOLTU
Q06327, LOX1_ARATHP29114, LOX1_HORVUP38414, LOX1_LENCU
Q76I22, LOX1_ORYSJP29250, LOX2_ORYSJP14856, LOX2_PEA
P09439, LOX2_SOYBNQ7G794, LOX3_ORYSJP09918, LOX3_PEA
P09186, LOX3_SOYBNQ53RB0, LOX4_ORYSJP38417, LOX4_SOYBN
Q9LUW0, LOX5_ARATHP27480, LOXA_PHAVUP38415, LOXA_SOLLC
P27481, LOXB_PHAVUP38416, LOXB_SOLLCP24095, LOXX_SOYBN
Q8RNT4, LOX_PSEAIT0JRM4, MNLOX_COLGCP0CT92, MNLOX_NAKOS
G4NAP4, MNLOX_PYRO7

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 1.13.11.-
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