ENZYME entry: EC 1.13.12.15
| Accepted Name |
|---|
| 3,4-dihydroxyphenylalanine oxidative deaminase.
|
| Alternative Name(s) |
|---|
| DOPA oxidative deaminase. |
| DOPAODA. |
| Oxidative deaminase. |
| Reaction catalysed |
|---|
| 2 L-dopa + O(2) <=> 2 3,4-dihydroxyphenylpyruvate + 2 NH(3) |
| Comment(s) |
|---|
- One of the three enzymes involved in L-dopa (3,4-
dihydroxyphenylalanine) catabolism in the non-oxygenic phototrophic
bacterium Rubrivivax benzoatilyticus OU5 (and not Rhodobacter
sphaeroides OU5 as had been thought), the other two being EC 4.3.1.22
and EC 2.6.1.49.
- In addition to DOPA, the enzyme can also use L-tyrosine,
L-phenylalanine, L-tryptophan and glutamate as substrate, but more
slowly.
- Inhibited by NADH and 2-oxoglutarate.
|
| Cross-references |
|---|
| BRENDA | 1.13.12.15 |
| EC2PDB | 1.13.12.15 |
| ExplorEnz | 1.13.12.15 |
| PRIAM enzyme-specific profiles | 1.13.12.15 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.13.12.15 |
| IUBMB Enzyme Nomenclature | 1.13.12.15 |
| IntEnz | 1.13.12.15 |
| MEDLINE | Find literature relating to 1.13.12.15 |
| MetaCyc | 1.13.12.15 |
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.13.12.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.13.-.-
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 1.-.-.-