ENZYME

ENZYME entry: EC 1.13.12.19

Accepted Name

2-oxuglutarate dioxygenase (ethylene-forming).

Alternative Name(s)

Ethylene-forming enzyme.

Reaction catalysed

2-oxoglutarate + O(2) <=> ethylene + 3 CO(2) + H(2)O

Comment(s)

This is one of two simultaneous reactions catalyzed by the enzyme, which is responsible for ethylene production in bacteria of the Pseudomonas syringae group.
In the other reaction (EC 1.14.11.34) the enzyme catalyzes the mono- oxygenation of both 2-oxoglutarate and L-arginine, forming succinate, carbon dioxide and L-hydroxyarginine, which is subsequently cleaved into guanidine and (S)-1-pyrroline-5-carboxylate.
The enzymes catalyze two cycles of the ethylene-forming reaction for each cycle of the succinate-forming reaction, so that the stoichiometry of the products ethylene and succinate is 2:1.

Cross-references

BRENDA

EC2PDB

ExplorEnz

PRIAM enzyme-specific profiles

KEGG Ligand Database for Enzyme Nomenclature

IUBMB Enzyme Nomenclature