ID 1.13.99.3 DE tryptophan 2'-dioxygenase. AN indole-3-alkane alpha-hydroxylase. AN tryptophan side-chain alpha,beta-oxidase. AN tryptophan side-chain oxidase. AN TSO. CA H(+) + L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH4(+). CC -!- Acts on a number of indole-3-alkane derivatives, oxidizing the CC 3-side-chain in the 2'-position. CC -!- Best substrates are L-tryptophan and 5-hydroxy-L-tryptophan. //