ENZYME entry: EC 1.14.11.26
| Accepted Name |
|---|
| Deacetoxycephalosporin-C hydroxylase.
|
| Alternative Name(s) |
|---|
| 3'-methylcephem hydroxylase. |
| DACS. |
| DAOC hydroxylase. |
| Deacetoxycephalosporin C hydroxylase. |
| Deacetylcephalosporin C synthase. |
| Reaction catalysed |
|---|
| Deacetoxycephalosporin C + 2-oxoglutarate + O(2) <=> deacetylcephalosporin C + succinate + CO(2) |
| Cofactor(s) |
|---|
| Iron.
|
| Comment(s) |
|---|
- The enzyme can also use 3-exomethylenecephalosporin C as a substrate
to form deacetoxycephalosporin C, although more slowly.
- In Acremonium chrysogenum, the enzyme forms part of a bifunctional
protein along with EC 1.14.20.1.
- It is a separate enzyme in Streptomyces clavuligerus.
|
| Cross-references |
|---|
| PROSITE | PDOC00165 ; PDOC51471 |
| BRENDA | 1.14.11.26 |
| EC2PDB | 1.14.11.26 |
| ExplorEnz | 1.14.11.26 |
| PRIAM enzyme-specific profiles | 1.14.11.26 |
| KEGG Ligand Database for Enzyme Nomenclature | 1.14.11.26 |
| IUBMB Enzyme Nomenclature | 1.14.11.26 |
| IntEnz | 1.14.11.26 |
| MEDLINE | Find literature relating to 1.14.11.26 |
| MetaCyc | 1.14.11.26 |
| UniProtKB/Swiss-Prot |
|
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