ENZYME entry: EC 1.14.11.37

Accepted Name
Kanamycin B dioxygenase.
Reaction catalysed
Kanamycin B + 2-oxoglutarate + O(2) <=> 2'-dehydrokanamycin A + succinate + NH(3) + CO(2)
Cofactor(s)
Fe(2+); L-ascorbate.
Comment(s)
Found in the bacterium Streptomyces kanamyceticus where it is involved in the conversion of the aminoglycoside antibiotic kanamycin B to kanamycin A.
Cross-references
BRENDA1.14.11.37
EC2PDB1.14.11.37
ExplorEnz1.14.11.37
PRIAM enzyme-specific profiles1.14.11.37
KEGG Ligand Database for Enzyme Nomenclature1.14.11.37
IUBMB Enzyme Nomenclature1.14.11.37
IntEnz1.14.11.37
MEDLINEFind literature relating to 1.14.11.37
MetaCyc1.14.11.37
UniProtKB/Swiss-Prot
Q6L732, KANJ_STRKN

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