ENZYME entry: EC 1.14.11.38

Accepted Name
Verruculogen synthase.
Reaction catalysed
Fumitremorgin B + 2-oxoglutarate + 2 O(2) + AH(2) <=> verruculogen + succinate + CO(2) + H(2)O + A
Cofactor(s)
Fe(2+).
Comment(s)
  • Found in the fungus Aspergillus fumigatus.
  • Both atoms of a dioxygen molecule are incorporated into verruculogen.
  • Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgin A.
Cross-references
BRENDA1.14.11.38
EC2PDB1.14.11.38
ExplorEnz1.14.11.38
PRIAM enzyme-specific profiles1.14.11.38
KEGG Ligand Database for Enzyme Nomenclature1.14.11.38
IUBMB Enzyme Nomenclature1.14.11.38
IntEnz1.14.11.38
MEDLINEFind literature relating to 1.14.11.38
MetaCyc1.14.11.38
UniProtKB/Swiss-Prot
B9WZX5, FTMF_ASPFM;  Q4WAW9, FTMF_ASPFU;  A1DA64, FTMF_NEOFI;  

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