ENZYME entry: EC 1.14.11.45

Accepted Name
L-isoleucine 4-hydroxylase.
Reaction catalysed
L-isoleucine + 2-oxoglutarate + O(2) <=> (4S)-4-hydroxy-L-isoleucine + succinate + CO(2)
Comment(s)
The enzyme, characterized from the bacterium Bacillus thuringiensis, can also catalyze the hydroxylation of L-leucine, L-norvaline, L-norleucine, and L-allo-isoleucine, as well as the sulfoxidation of L-methionine, L-ethionine, S-methyl-L-cysteine, S-ethyl-L-cysteine, and S-allyl-L-cysteine.
Cross-references
BRENDA1.14.11.45
EC2PDB1.14.11.45
ExplorEnz1.14.11.45
PRIAM enzyme-specific profiles1.14.11.45
KEGG Ligand Database for Enzyme Nomenclature1.14.11.45
IUBMB Enzyme Nomenclature1.14.11.45
IntEnz1.14.11.45
MEDLINEFind literature relating to 1.14.11.45
MetaCyc1.14.11.45
UniProtKB/Swiss-Prot
E2GIN1, IDO_BACTU

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