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ENZYME

ENZYME entry: EC 1.14.11.54

Accepted Name
mRNA N(1)-methyladenine demethylase
Alternative Name(s)
ALKBH3
Reaction catalysed
2-oxoglutarate + an N(1)-methyladenosine in mRNA + O2 = an adenosine in mRNA + CO2 + formaldehyde + succinate
Comment(s)
  • Catalyzes oxidative demethylation of mRNA N(1)-methyladenine.
  • The enzyme is also involved in alkylation repair in DNA.
Cross-references
BRENDA1.14.11.54
EC2PDB1.14.11.54
ExplorEnz1.14.11.54
PRIAM enzyme-specific profiles1.14.11.54
KEGG Ligand Database for Enzyme Nomenclature1.14.11.54
IUBMB Enzyme Nomenclature1.14.11.54
IntEnz1.14.11.54
MEDLINEFind literature relating to 1.14.11.54
MetaCyc1.14.11.54
Rhea expert-curated reactions1.14.11.54
UniProtKB/Swiss-Prot
Q32L00, ALKB3_BOVINQ96Q83, ALKB3_HUMANQ8K1E6, ALKB3_MOUSE
Q5XIC8, ALKB3_RAT

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